Format

Send to

Choose Destination
Nat Rev Cancer. 2014 Aug;14(8):511-2. doi: 10.1038/nrc3765.

Host-microbe interactions and spatial variation of cancer in the gut.

Abstract

The small intestine has a greater cell mass than the colon, it is longer and with greater surface area and has a faster rate of epithelial turnover. At first, this might suggest that the small bowel epithelium could be at greater risk of the cumulative genetic errors that predispose to cancer. However, the incidence of cancer of the small bowel is more than tenfold lower than that of colorectal cancer.

PMID:
25202783
DOI:
10.1038/nrc3765
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center