Format

Send to

Choose Destination
J Musculoskelet Neuronal Interact. 2014 Sep;14(3):276-85.

Osteogenic effects of a physical activity intervention in South African black children.

Author information

1
Exercise Laboratory, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Abstract

OBJECTIVES:

To determine whether a weight-bearing physical activity intervention improves measures of bone density, size and strength in a pre- and early pubertal cohort of black South African children.

METHODS:

Twenty two school children (9.7±1.1 years) were cluster randomised into an exercise (EX; n=12) and control (CON; n=10) group. EX children performed a weight-bearing exercise program for 20 weeks. CON children continued their regular activities. Whole body DXA and tibial peripheral QCT scans were obtained. Urine was analysed for concentrations of cross-linked N-telopeptides of Type I collagen (NTX).

RESULTS:

Changes in 4% volumetric BMD, area and strength were greater in EX than CON. At the 38% site, change in bone area and density was greater in EX than CON. The greater change in periosteal circumference in the EX groups also resulted in a greater change in cortical thickness of the tibia compared to the CON group. NTX concentration was lower in the EX group than the CON group after the intervention.

CONCLUSIONS:

This study documents for the first time the beneficial response of trabecular and cortical bone of black children to a weight bearing exercise intervention.

PMID:
25198222
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for International Society of Musculoskeletal and Neuronal Interactions
Loading ...
Support Center