Format

Send to

Choose Destination
Pediatr Dent. 2014 Jul-Aug;36(4):302-8.

A comparison of sedation-related events for two multiagent oral sedation regimens in pediatric dental patients.

Author information

1
Dentist in private practice, Irvine, Calif.; USA. laura@lauradds.com.
2
Advanced Education Program in Pediatric Dentistry, Department of Pediatric Dentistry, at Loma Linda University School of Dentistry, Loma Linda, Calif.; USA.
3
Advanced Education Program in Dental Anesthesiology, Department of Dental Anesthesiology, at Loma Linda University School of Dentistry, Loma Linda, Calif.; USA.

Abstract

PURPOSE:

This study compared the incidence of adverse sedation-related events occurring with two different multiagent oral sedation regimens in pediatric dental patients.

METHODS:

Forty healthy patients (three to six years old), received either a sedation regimen of chloral hydrate, meperidine, and hydroxyzine with nitrous oxide (CH/M/H/N2O; N=19) or a regimen of midazolam, meperidine, and hydroxyzine with nitrous oxide (MZ/M/H/N2O; N=21). The two treating dentists answered a questionnaire regarding the perioperative period. Parents received two phone interviews at eight and 24 hours after sedation. Statistical analysis included chi-square, Pearson correlation coefficient, and t-test (P<.05).

RESULTS:

Children sedated with MZ/M/H/N2O showed a significant increase in hyperactivity during dental treatment, slurring/difficulty speaking, and difficulty walking postoperatively within eight hours after discharge. Children sedated with CH/M/H/N2O showed a significant increase in frequency of sleeping, talking less than normal after arriving home, and an increased need for postoperative pain medication.

CONCLUSIONS:

Different oral sedation regimens produce different adverse sedation-related events. The provider of pediatric oral sedation should select a sedative regimen with an adverse sedation-related profile that he/she believes is optimal for the patient being treated. Parents should be counseled as to possible postsedation effects anticipated based on the sedative regimen administered.

PMID:
25197995
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Ingenta plc
Loading ...
Support Center