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Stand Genomic Sci. 2014 Feb 15;9(3):744-54. doi: 10.4056/sigs.5048907. eCollection 2014 Jun 15.

Draft genome sequences and description of Lactobacillus rhamnosus strains L31, L34, and L35.

Author information

1
Interdisciplinary Program of Medical Microbiology, Graduate School, Chulalongkorn University, Bangkok, Thailand.
2
Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas, USA ; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, USA.
3
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
4
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA ; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
5
Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
6
Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas, USA ; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, USA ; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.

Abstract

Lactobacillus rhamnosus is a facultative, lactic acid bacterium in the phylum Firmicutes. Lactobacillus spp. are generally considered beneficial, and specific strains of L. rhamnosus are validated probiotics. We describe the draft genomes of three L. rhamnosus strains (L31, L34, and L35) isolated from the feces of Thai breastfed infants, which exhibit anti-inflammatory properties in vitro. The three genomes range between 2.8 - 2.9 Mb, and contain approximately 2,700 protein coding genes.

KEYWORDS:

Lactobacillus rhamnosus; anti-inflammatory; comparative genomics; lactic acid bacteria; probiotics

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