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Braz J Infect Dis. 2015 Jan-Feb;19(1):85-9. doi: 10.1016/j.bjid.2014.07.006. Epub 2014 Sep 1.

Severe infective endocarditis with systemic embolism due to community associated methicillin-resistant Staphylococcus aureus ST630.

Author information

1
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
2
Department of Pharmacy, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
3
Ningbo Institute of Microcirculation and Henbane, Ningbo, China.
4
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China. Electronic address: xiao-yonghong@163.com.

Abstract

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly causing infective endocarditis over the past decade. Here we report a healthy man who developed a severe acute infective endocarditis with systemic embolism caused by CA-MRSA. The strain was recovered from repeated blood cultures and was characterized using molecular detection and genotyping. The S. aureus isolate was typed as ST630 SCCmecV with spa-type t4549, agrI/IV and was PVL-negative. This is the only case report, to our knowledge, of CA-MRSA infective endocarditis in China. This case highlights the emergence and geographical spread of life-threatening CA-MRSA infection within China.

KEYWORDS:

Community-acquired MRSA; Infective endocarditis; ST 630; Surgical therapy

PMID:
25193080
DOI:
10.1016/j.bjid.2014.07.006
[Indexed for MEDLINE]
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