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Hum Cell. 1989 Sep;2(3):297-303.

[Establishment and characterization of five human myeloma cell lines].

[Article in Japanese]

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Department of Medicine, Kawasaki Medical School, Kurashiki, Japan.


Since 1980 five human myeloma cell lines, KMM-1, KMS-5, KMS-11, KMS-12-PE and KMS-12-BM, have been established in Kawasaki Medical School. Histologically, all the cell lines resembled plasma cells and were EBNA negative. KMM-1, KMS-11, KMS-12-PE and KMS-12-BM reacted with PCA-1, while KMM-1, KMS-12-PE and KMS-12-BM with CD38. KMM-1 and KMS-11 secreted immunoglobulins into culture medium. Karyologically, all the cell lines were abnormal. Only KMS-5 was tumorigenic when transplanted subcutaneously into nude mice.

[Indexed for MEDLINE]

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