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Probl Radiac Med Radiobiol. 2013;(18):169-72.

Multiple myeloma among Chornobyl accident clean-up workers - state and perspectives of analytical study.

[Article in English, Ukrainian; Abstract available in Ukrainian from the publisher]

Abstract

in English, Ukrainian

The objective of the study was to analyze the Multiple Myeloma (MM) incidence in clean-up workers preparing the information background for consequent analytical study with a dose-dependent risk estimates.

MATERIALS AND METHODS:

The Cohort Database was linked to the Ukrainian National Cancer Registry to identify the MM cases in a cohort of 152 520 male clean-up workers.

RESULTS:

The 64 MM cases were identified in the studied Cohort for the 1987-2012 period. Fifty-eight of them were included to the preliminary incidence analysis accounting for the 10-years lag-period. According to the preliminary data analysis the MM incidence rate in studied clean-up workers Cohort did not exceed the corresponding rate in general population of Ukraine along the 21 years after the catastrophe.

CONCLUSIONS:

Standardized incidence ratio for the 2008-2012 period, that is 22-26 years after the accident, demonstrated the significant excess of MM incidence among male clean-up workers in comparison with general population of Ukraine of corresponding age and gender (SIR 1.61, 95% CI 1.01;2.21).

KEYWORDS:

Chornobyl accident; clean-up workers; incidence; multiple myeloma

PMID:
25191721
[Indexed for MEDLINE]

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