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Front Microbiol. 2014 Aug 21;5:437. doi: 10.3389/fmicb.2014.00437. eCollection 2014.

Bifidobacterium bifidum as an example of a specialized human gut commensal.

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Alimentary Pharmabiotic Centre and Department of Microbiology, Bioscience Institute, National University of Ireland Cork, Ireland.
Laboratory of Probiogenomics, Department of Life Sciences, University of Parma Parma, Italy.
Department of Food, Environmental and Nutritional Sciences, University of Milan Milan, Italy.


Bifidobacteria are considered dominant and for this reason key members of the human gut microbiota, particularly during the first one to two years following birth. A substantial proportion of the bifidobacterial population in the intestine of infants belong to the Bifidobacterium bifidum taxon, whose members have been shown to display remarkable physiological and genetic features involving adhesion to epithelia, as well as utilization of host-derived glycans. Here, we reviewed the current knowledge on the genetic features and associated adaptations of B. bifidum to the human gut.


Bifidobacterium bifidum; bifidobacteria; genomics; microbiota; probiotics

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