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J Foot Ankle Surg. 2016 Mar-Apr;55(2):276-8. doi: 10.1053/j.jfas.2014.07.005. Epub 2014 Sep 1.

Bilateral Achilles Tendon Ruptures Associated With Ciprofloxacin Use in the Setting of Minimal Change Disease: Case Report and Review of the Literature.

Author information

1
Resident, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
2
Resident, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address: km34@aub.edu.lb.
3
Clinical Senior Lecturer, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Abstract

Fluoroquinolones are widely used antibiotics; however, numerous side effects have been reported in published studies, including a spectrum of tendinopathies, affecting numerous anatomic sites. Several risk factors have been identified, including advanced age (>60 years), corticosteroid use, renal failure or dialysis, female sex, and nonobesity. We present the case of an elderly male with minimal change disease treated with glucocorticoids and acute kidney injury, who sustained spontaneous nontraumatic bilateral Achilles tendon tears 4 days after initiating ciprofloxacin.

KEYWORDS:

Achilles tendon; minimal change disease; quinolone; rupture

PMID:
25189336
DOI:
10.1053/j.jfas.2014.07.005
[Indexed for MEDLINE]

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