Format

Send to

Choose Destination
Crit Care. 2014 Aug 27;18(4):461. doi: 10.1186/s13054-014-0461-9.

There's life in the old dog yet: vitamin C as a therapeutic option in endothelial dysfunction.

Author information

1
Institute of Biological Chemistry and Nutrition, University of Hohenheim, Garbenstra├če 30, 70599, Stuttgart, Germany. Sandra.Rodemeister@uni-hohenheim.de.
2
Institute of Biological Chemistry and Nutrition, University of Hohenheim, Garbenstra├če 30, 70599, Stuttgart, Germany. hans-K.biesalski@uni-hohenheim.de.

Abstract

The use of vitamin C against different diseases has been controversially and emotionally discussed since Linus Pauling published his cancer studies. In vitro and animal studies showed promising results and explained the impact of vitamin C, particularly in cases with endothelial dysfunction. Indeed, studies (reviewed in this issue of Critical Care by Oudemans-van Straaten and colleagues) using high-dose vitamin C and the parenteral route of application seem to be more successful than oral vitamin C delivery.

Comment on

PMID:
25184406
PMCID:
PMC4423636
DOI:
10.1186/s13054-014-0461-9
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center