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Ophthalmology. 2014 Dec;121(12):2311-6. doi: 10.1016/j.ophtha.2014.07.015. Epub 2014 Aug 30.

Corneal sensation and dry eye symptoms after conventional versus inverted side-cut femtosecond LASIK: a prospective randomized study.

Author information

1
Byers Eye Institute, Stanford University School of Medicine, Stanford, California.
2
Byers Eye Institute, Stanford University School of Medicine, Stanford, California. Electronic address: Edward.Manche@stanford.edu.

Abstract

PURPOSE:

To compare corneal sensation and self-reported dry eye symptoms after femtosecond-assisted LASIK with conventional versus inverted side cuts.

DESIGN:

Prospective, randomized, eye-to-eye study.

PARTICIPANTS:

A total of 120 eyes in 60 participants with myopia.

METHODS:

Fellow eyes were randomized to receive femtosecond-assisted LASIK with a conventional 70-degree side cut made with the 60 kHz IntraLase FS (Abbott Medical Optics, Santa Ana, CA) or an inverted 130-degree side cut made with the 150 kHz IntraLase iFS (Abbott Medical Optics). Cochet-Bonnet aesthesiometry (Luneau Ophthalmologia, Chartes, France) measured corneal sensation (60 mm = normal sensation; <60 mm = depressed sensation) preoperatively and at postoperative months 1, 3, 6, and 12. Participants also completed serial dry eye surveys using the same subscales (frequency, severity, bothersome) as the validated, Rasch-tested, linear-scaled Quality of Vision questionnaire.

MAIN OUTCOME MEASURES:

Objective corneal sensation and self-reported light sensitivity, dryness, foreign body sensation, and pain/discomfort.

RESULTS:

Preoperative corneal sensation as measured by mean Cochet-Bonnet aethesiometry was equal between the inverted and conventional side cut groups but was better in eyes with an inverted side cut compared with a conventional side cut at all postoperative months (inverted vs. conventional: 1 month, 14.5 vs. 13.2 mm; 3 months, 24.9 vs. 18.4 mm; 6 months, 51.2 vs. 42.6 mm; 12 months, 59.8 vs. 58.3 mm; all P ≤ 0.02). None of the subjective dry eye parameters demonstrated statistically significant differences between the groups at any time point.

CONCLUSIONS:

The LASIK flaps with an inverted side cut are associated with superior recovery of corneal sensation compared with flaps with a conventional side cut during the first postoperative year; however, this may not translate to significant improvements in subjective dry eye symptoms.

PMID:
25178805
DOI:
10.1016/j.ophtha.2014.07.015
[Indexed for MEDLINE]

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