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G Chir. 2014 Jul-Aug;35(7-8):195-8.

From surgery to neurosurgery: our experience on the efficacy of fleece-bound sealing (TachoSil®) for dural repair.

Abstract

AIM:

To report on our routine use of TachoSil® for dural repair in neurosurgical practice.

METHOD:

TachoSil® has been applied in different fields of surgery thus far. When using TachoSil®, fibrinogen and thrombin is provided locally at the site of the dural defects. Upon contact with fluid, the clotting factors of TachoSil® dissolve and form a fibrin network, which glues the collagen sponge to the wound surface.

RESULTS:

In our experience, TachoSil® was found to be effective as support for the suture of the dura in patients undergoing spinal and cranial neurosurgical operations. Two illustrative examples are shown.

CONCLUSIONS:

Our procedure showed that closing the dural defect with TachoSil® is a technically simple, reliable and safe method for patients. Indeed, no post-operative cerebrospinal fluid leakage was observed. Nonetheless, further studies with larger sample size are warranted to confirm the efficacy of TachoSil® patches for dural repair.

PMID:
25174296
PMCID:
PMC4321528
[Indexed for MEDLINE]
Free PMC Article

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