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Phytomedicine. 2014 Sep 25;21(11):1349-55. doi: 10.1016/j.phymed.2014.06.014. Epub 2014 Aug 9.

The effects of repeated administration of camphor-crataegus berry extract combination on blood pressure and on attentional performance - a randomized, placebo-controlled, double-blind study.

Author information

1
Department of Psychology, Ludwig-Maximilians-University Munich, Leopoldstr. 13, D-80802 Munich, Germany.
2
Department of Psychology, Ludwig-Maximilians-University Munich, Leopoldstr. 13, D-80802 Munich, Germany. Electronic address: schandry@lmu.de.

Abstract

The present study investigated the effects of repeated administration of Korodin(®), a combination of camphor and crataegus berry extract, on blood pressure and attentional functioning. This study was conducted based on a randomized, placebo-controlled, double-blind design. 54 persons participated (33 female, 21 male) with a mean age of 24.3 years. Blood pressure and body mass index were in the normal range. Participants received 20 drops of either Korodin(®) or a placebo for four times with interjacent time intervals of about 10 min. Blood pressure was measured sphygmomanometrically before and after each administration. Attentional performance was quantified by using two paper-and-pencil tests, the d2 Test of Attention and Digit Symbol Test. Greater increases in blood pressure occurred after the four Korodin(®) administrations in comparison to the four placebo administrations. The performance in two parameters of d2 Test of Attention was consistently superior after the intake of Korodin(®). The excellent tolerability and safety of Korodin(®), even after a total consumption of 80 drops, was confirmed.

KEYWORDS:

Blood pressure; Camphor; Cognitive function; Complaints; Crataegus berry

PMID:
25172798
DOI:
10.1016/j.phymed.2014.06.014
[Indexed for MEDLINE]

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