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Helicobacter. 2014 Sep;19 Suppl 1:11-8. doi: 10.1111/hel.12160.

Pathogenesis of Helicobacter pylori infection.

Author information

1
Department of Biology, University of Padova, Padova, Italy.

Abstract

Helicobacter pylori relies on multiple colonization and virulence factors to persist in the human stomach for life. In addition, these factors can be modulated and vary to suit the ever-changing environment within the host individual. This article outlines the novel developments in this field of research during the past year, highlighting the cag pathogenicity island, VacA, γ-glutamyl-transpeptidase as well as including recent advances in protein structure, bacteria-host interaction, and the role of stomach microbiota.

KEYWORDS:

CagA; Type IV secretion system; VacA; cancerogenesis; γ-glutamyl-transpeptidase

PMID:
25167940
DOI:
10.1111/hel.12160
[Indexed for MEDLINE]
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