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Clin Infect Dis. 2015 Jan 1;60(1):e1-3. doi: 10.1093/cid/ciu681. Epub 2014 Aug 27.

Valley fever: finding new places for an old disease: Coccidioides immitis found in Washington State soil associated with recent human infection.

Author information

1
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
2
Washington State Department of Health, Shoreline and Tumwater.
3
Benton-Franklin Health District, Kennewick, Washington.
4
Translational Genomics Research Institute, Flagstaff, Arizona.
5
Coccidioidomycosis Serology Laboratory, University of California, Davis.

Abstract

We used real-time polymerase chain reaction and culture to demonstrate persistent colonization of soils by Coccidioides immitis, an agent of valley fever, in Washington State linked to recent human infections and located outside the endemic range. Whole-genome sequencing confirmed genetic identity between isolates from soil and one of the case-patients.

KEYWORDS:

Coccidioides; WGS typing; soil detection; valley fever

PMID:
25165087
PMCID:
PMC4296125
DOI:
10.1093/cid/ciu681
[Indexed for MEDLINE]
Free PMC Article

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