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Dev Cell. 2014 Aug 25;30(4):365-6. doi: 10.1016/j.devcel.2014.08.013.

Cutting through the noise: the mechanics of intracellular transport.

Author information

1
Biophysical Sciences Graduate Program, University of Chicago, Chicago, IL 60637, USA; James Franck Institute and Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637, USA.
2
James Franck Institute and Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637, USA; Department of Physics, University of Chicago, Chicago, IL 60637, USA. Electronic address: gardel@uchicago.edu.

Abstract

Intracellular transport of organelles and proteins is driven by multiple ATP-dependent processes. Recently in Cell, Guo et al. (2014) developed a technique, force-spectrum microscopy, to measure intracellular forces and demonstrate that large motion of cellular components can be produced by random ATP-dependent fluctuations within the cytoplasm.

PMID:
25158851
DOI:
10.1016/j.devcel.2014.08.013
[Indexed for MEDLINE]
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