Format

Send to

Choose Destination
Clin Perinatol. 2014 Sep;41(3):487-502. doi: 10.1016/j.clp.2014.05.001. Epub 2014 Jul 22.

Acute kidney injury in the neonate.

Author information

1
Division of Nephrology, Dialysis and Transplantation, University of Iowa Children's Hospital, 200 Hawkins Drive, 4023 BT, Iowa City, IA 52242, USA.
2
Division of Pediatric Nephrology, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder Building 516, Birmingham, AL 35233, USA. Electronic address: daskenazi@peds.uab.edu.

Abstract

Critically ill neonates are at risk for acute kidney injury (AKI). AKI has been associated with increased risk of morbidity and mortality in adult and pediatric patients, and increasing evidence suggests a similar association in the neonatal population. This article describes the current AKI definitions (including their limitations), work on novel biomarkers to define AKI, diagnosis and management strategies, long-term outcomes after AKI, and future directions for much-needed research in this important area.

KEYWORDS:

Acute kidney injury; Acute renal failure; Biomarkers; Chronic kidney disease; Critical illness; Neonate

PMID:
25155722
DOI:
10.1016/j.clp.2014.05.001
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center