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PLoS One. 2014 Aug 22;9(8):e105090. doi: 10.1371/journal.pone.0105090. eCollection 2014.

Standing at the gateway to Europe--the genetic structure of Western balkan populations based on autosomal and haploid markers.

Author information

1
Estonian Biocentre and Department of Evolutionary Biology, University of Tartu, Estonia; Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and Herzegovina; Institute of Biochemistry and Genetics, Ufa Research Centre, RAS, Ufa, Bashkortostan, Russia.
2
Estonian Biocentre and Department of Evolutionary Biology, University of Tartu, Estonia.
3
Estonian Biocentre and Department of Evolutionary Biology, University of Tartu, Estonia; Institute of Biochemistry and Genetics, Ufa Research Centre, RAS, Ufa, Bashkortostan, Russia.
4
Faculty of Pharmacy, University of Sarajevo; Bosnia and Herzegovina.
5
University Center of Forensic Science, Split, Croatia.
6
Genos doo, Zagreb, Croatia.
7
Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
8
Institute for forensic medicine, criminology and and medical deontology, Medical Faculty, University of St. Cyril and Methodius, Skopje, F.Y.R of Macedonia.
9
National forensic laboratory, Ministry of the Interior, Slovenia.
10
Forensic Center, Police Directorate, Danilovgrad, Montenegro.
11
Croatian Academy of Science and Art, Zagreb, Croatia.
12
Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and Herzegovina; University Center of Forensic Science, Split, Croatia.

Abstract

Contemporary inhabitants of the Balkan Peninsula belong to several ethnic groups of diverse cultural background. In this study, three ethnic groups from Bosnia and Herzegovina - Bosniacs, Bosnian Croats and Bosnian Serbs - as well as the populations of Serbians, Croatians, Macedonians from the former Yugoslav Republic of Macedonia, Montenegrins and Kosovars have been characterized for the genetic variation of 660 000 genome-wide autosomal single nucleotide polymorphisms and for haploid markers. New autosomal data of the 70 individuals together with previously published data of 20 individuals from the populations of the Western Balkan region in a context of 695 samples of global range have been analysed. Comparison of the variation data of autosomal and haploid lineages of the studied Western Balkan populations reveals a concordance of the data in both sets and the genetic uniformity of the studied populations, especially of Western South-Slavic speakers. The genetic variation of Western Balkan populations reveals the continuity between the Middle East and Europe via the Balkan region and supports the scenario that one of the major routes of ancient gene flows and admixture went through the Balkan Peninsula.

PMID:
25148043
PMCID:
PMC4141785
DOI:
10.1371/journal.pone.0105090
[Indexed for MEDLINE]
Free PMC Article

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