Format

Send to

Choose Destination
Science. 2014 Aug 22;345(6199):909-12. doi: 10.1126/science.1251959.

Nanoparticle imaging. Electron microscopy of gold nanoparticles at atomic resolution.

Author information

1
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
2
Department of Chemistry, Nanoscience Center, University of Jyväskylä, FI-40014 Jyväskylä, Finland.
3
Department of Physics, Nanoscience Center, University of Jyväskylä, FI-40014 Jyväskylä, Finland.
4
Physical Bioscience Division, Lawrence Berkeley National Lab, Berkeley, CA 94720, USA.
5
Stanford Nanocharacterization Laboratory, Stanford University, Stanford, CA 94305, USA.
6
Catalysis Research Center, Hokkaido University, Sapporo, Japan.
7
Department of Chemistry, Nanoscience Center, University of Jyväskylä, FI-40014 Jyväskylä, Finland. Department of Physics, Nanoscience Center, University of Jyväskylä, FI-40014 Jyväskylä, Finland.
8
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. kornberg@stanford.edu.

Abstract

Structure determination of gold nanoparticles (AuNPs) is necessary for understanding their physical and chemical properties, but only one AuNP larger than 1 nanometer in diameter [a 102-gold atom NP (Au102NP)] has been solved to atomic resolution. Whereas the Au102NP structure was determined by x-ray crystallography, other large AuNPs have proved refractory to this approach. Here, we report the structure determination of a Au68NP at atomic resolution by aberration-corrected transmission electron microscopy, performed with the use of a minimal electron dose, an approach that should prove applicable to metal NPs in general. The structure of the Au68NP was supported by small-angle x-ray scattering and by comparison of observed infrared absorption spectra with calculations by density functional theory.

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center