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Mem Inst Oswaldo Cruz. 2014 Sep;109(6):820-3. Epub 2014 Aug 19.

Molecular detection of Mayaro virus during a dengue outbreak in the state of Mato Grosso, Central-West Brazil.

Author information

1
Faculdade de Medicina, Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil.
2
MT Laboratório, Secretaria Estadual de Saúde, Cuiabá, MT, Brasil.

Abstract

Mayaro virus (MAYV) is frequently reported in Pan-Amazonia. The aim of this study was to investigate the circulation of alphaviruses during a dengue outbreak in the state of Mato Grosso, Brazil. Serum samples from dengue-suspected patients were subjected to multiplex semi-nested reverse transcriptase polymerase chain reaction for 11 flaviviruses and five alphaviruses, to nucleotide sequencing and to viral isolation. MAYV was detected in 15 (2.5%) of 604 patients. Twelve were co-infected with dengue virus 4, which was isolated from 10 patients. The molecular detection of MAYV in dengue-suspected patients suggests that other arboviruses may be silently circulating during dengue outbreaks in Brazil.

PMID:
25141284
PMCID:
PMC4238776
DOI:
10.1590/0074-0276140108
[Indexed for MEDLINE]
Free PMC Article

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