Format

Send to

Choose Destination
Clin Infect Dis. 2014 Nov 15;59(10):1451-4. doi: 10.1093/cid/ciu658. Epub 2014 Aug 18.

High usage of topical fusidic acid and rapid clonal expansion of fusidic acid-resistant Staphylococcus aureus: a cautionary tale.

Author information

1
Department of Molecular Medicine and Pathology, University of Auckland Institute of Environmental Science and Research, Wellington Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
2
Alere Technologies, Jena Institute for Medical Microbiology and Hygiene, Dresden, Germany.
3
Institute of Environmental Science and Research, Wellington.
4
Department of Molecular Medicine and Pathology, University of Auckland.
5
Department of Clinical Microbiology, Auckland District Health Board.
6
LabTests Auckland, New Zealand.
7
Department of Molecular Medicine and Pathology, University of Auckland Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.

Abstract

Our aim was to assess national prescribing trends and determine longitudinal resistance patterns for topical antimicrobials in New Zealand. We observed a dramatic increase in fusidic acid (FA) resistance, and clonal expansion of FA-resistant Staphylococcus aureus. This increase was concurrent with a significant national increase in topical FA dispensing.

KEYWORDS:

MRSA; antimicrobial resistance; antimicrobial use; epidemiology; fusC

PMID:
25139961
DOI:
10.1093/cid/ciu658
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center