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Oman J Ophthalmol. 2014 May;7(2):90-2. doi: 10.4103/0974-620X.137170.

OLOGEN(®) implant in the management of glaucoma in an unusual case of Axenfeld-Rieger syndrome.

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Department of Ophthalmology, Padmashree Dr. D. Y. Patil University Pimpri, Pune, Maharashtra, India.
Natasha Eyecare and Research Centre, Sai Saheb Bldg. Pimple Saudagar, Pune, Maharashtra, India.


We report an unusual case of Axenfeld-Rieger Syndrome with secondary glaucoma managed with Ologen(®) implant. A 35-year-old male presented with complaints of decreased vision in both eyes of 22 years duration. His best corrected visual acuity (BCVA) was no perception of light in right eye and 20/30 in left eye. Gonioscopy revealed anterior insertion of iris into trabecular meshwork, prominent iris processes and broad-based synechiae with prominent Schwalbe's line along the angle circumference with cord-like structures taking its origin at the level of Schwalbe's line in both eyes. Fundus examination revealed total glaucomatous optic atrophy in right eye with 0.9:1 cup disc ratio with bipolar notch in left eye. Humphrey visual field analysis showed superior and inferior arcuate scotoma in left eye. Intraocular pressure measured by Goldman applanation tonometry was 30 mmHg and 26 mmHg in right and left eye, respectively. After an unsuccessful medical management, he underwent trabeculectomy with Ologen(®) implant under local anesthesia in his left eye. Postoperatively, at the end of one year, intraocular pressure (IOP) in his left eye was controlled without medication. This case highlights the management of secondary angle closure glaucoma in Axenfeld-Rieger syndrome with Ologen(®) implant.


Axenfeld–Rieger syndrome; Ologen®; biodegradable implant; glaucoma; trabeculectomy

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