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Antimicrob Agents Chemother. 2014 Nov;58(11):6928-30. doi: 10.1128/AAC.03855-14. Epub 2014 Aug 18.

Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids.

Author information

1
Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France.
2
Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France INSERM, U1016, Institut Cochin, Paris, France CNRS (UMR 8104), Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
3
Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France.
4
Institut Pasteur, Unité de Biologie des Bactéries Pathogènes à Gram Positif, Paris, France CNRS ERL3526, Paris, France.
5
Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France INSERM, U1016, Institut Cochin, Paris, France CNRS (UMR 8104), Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France claire.poyart@cch.aphp.fr.

Abstract

Among 1,827 group B Streptococcus (GBS) strains collected between 2006 and 2013 by the French National Reference Center for Streptococci, 490 (26.8%) strains were erythromycin resistant. The erm(T) resistance gene was found in six strains belonging to capsular polysaccharides Ia, III, and V and was carried by the same mobilizable plasmid, which could be efficiently transferred by mobilization to GBS and Enterococcus faecalis recipients, thus promoting a broad dissemination of erm(T).

PMID:
25136004
PMCID:
PMC4249376
DOI:
10.1128/AAC.03855-14
[Indexed for MEDLINE]
Free PMC Article

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