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Trop Med Int Health. 2014 Nov;19(11):1355-9. doi: 10.1111/tmi.12373. Epub 2014 Aug 19.

Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses.

Author information

1
Unité d'entomologie Médicale, Institut Pasteur de Dakar, Dakar, Senegal; Université Cheikh Anta Diop de Dakar, Dakar, Senegal.

Abstract

OBJECTIVE:

To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1.

METHODS:

We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates.

RESULTS:

The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%).

CONCLUSION:

Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.

KEYWORDS:

Aedes aegypti; Dakar; Kedougou; Kédougou; Senegal; Serotipos 1 y 3 del Dengue; Susceptibilidad Oral; Sénégal; dengue serotypes 1 and 3; oral susceptibility; susceptibilité orale; sérotypes 1 et 3 de la dengue

PMID:
25134541
DOI:
10.1111/tmi.12373
[Indexed for MEDLINE]
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