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J Clin Exp Neuropsychol. 2014;36(8):818-30. doi: 10.1080/13803395.2014.943695. Epub 2014 Aug 15.

Executive function late effects in survivors of pediatric brain tumors and acute lymphoblastic leukemia.

Author information

1
a Department of Pediatrics, Section of Psychology , Baylor College of Medicine , Houston , TX , USA.

Abstract

BACKGROUND:

Survivors of pediatric brain tumors (BT) and acute lymphoblastic leukemia (ALL) are at risk for neurocognitive late effects related to executive function.

PROCEDURE:

Survivors of BT (48) and ALL (50) completed neurocognitive assessment. Executive function was compared to estimated IQ and population norms by diagnostic group.

RESULTS:

Both BT and ALL demonstrated relative executive function weaknesses. As a group, BT survivors demonstrated weaker executive functioning than expected for age. Those BT survivors with deficits exhibited a profile suggestive of global executive dysfunction, while affected ALL survivors tended to demonstrate specific rapid naming deficits.

CONCLUSION:

Findings suggest that pediatric BT and ALL survivors may exhibit different profiles of executive function late effects, which may necessitate distinct intervention plans.

KEYWORDS:

Brain tumor; Executive function; Late effects; Leukemia; Pediatric

PMID:
25126830
PMCID:
PMC4229447
DOI:
10.1080/13803395.2014.943695
[Indexed for MEDLINE]
Free PMC Article
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