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Hippokratia. 2014 Jan;18(1):86-7.

De Quervain thyroiditis in the course of H1N1 influenza infection.

Author information

  • 1Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece.
  • 2Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece ; North Middlesex University Hospital NHS Trust, London, UK.

Abstract

BACKGROUND/AIM:

Viral infections have been frequently associated with subacute (De Quervain) thyroiditis and autoimmune thyroid diseases. In the present case report we document a rare case of De Quervain thyroiditis in the course of H1N1 influenza infection.

DESCRIPTION OF THE CASE:

A 17-year-old previously healthy female that was treated in the General Hospital of Kalamata developed an influenza-like syndrome that was accompanied by palpitations, thyroid enlargement, and increased C-reactive protein. Polymerase chain reaction assay confirmed the diagnosis of H1N1 virus infection. Serum thyroid-stimulating hormone was suppressed to zero while the levels of free thyroxine and triiodothyronine were increased. The patient was treated with non-steroidal anti-inflammatory drugs and thyroid function was gradually restored without evolving to a hypothyroid phase.

CONCLUSION:

To our knowledge this is the second case described in the literature of De Quervain thyroiditis associated with H1N1 influenza infection.

KEYWORDS:

De Quervain thyroiditis; H1N1 virus

PMID:
25125962
PMCID:
PMC4103053
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