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Antioxid Redox Signal. 2014 Nov 1;21(13):1819-22. doi: 10.1089/ars.2014.5959. Epub 2014 Sep 16.

Neonatal lung function and therapeutics.

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1
1 Department of Pediatrics, Duke University Medical Center , Durham, North Carolina.

Abstract

Respiratory diseases are increasingly recognized as having their origins during perinatal and early postnatal lung development, a time of significant adaptation to large changes in redox conditions as well as to mechanical forces. This Forum of the journal presents a Forum highlighting studies of the interplay between reactive oxygen/nitrogen species and the systems that have evolved to degrade them or exploit them, as well as the cellular repair processes which respond to early life redox stress in the lung. This group of authors suggests new understandings of these events that may point the way to improved therapeutic approaches.

PMID:
25111369
PMCID:
PMC4239672
DOI:
10.1089/ars.2014.5959
[Indexed for MEDLINE]
Free PMC Article
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