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Vaccine. 2014 Sep 22;32(42):5390-8. doi: 10.1016/j.vaccine.2014.07.073. Epub 2014 Aug 6.

The Vaccine Safety Datalink: successes and challenges monitoring vaccine safety.

Author information

1
Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: mmm2@cdc.gov.
2
Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
3
Marshfield Clinic Research Foundation, Marshfield, WI, United States.
4
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, United States.
5
Institute for Health Research, Kaiser Permanente, Denver, CO, United States.
6
HealthPartners Institute for Education and Research, Minneapolis, MN, United States.
7
Vaccine Study Center, Kaiser Permanente of Northern California, Oakland, CA, United States.
8
Center for Health Research, Kaiser Permanente Northwest, Portland, OR, United States.
9
Group Health Cooperative, Seattle, WA, United States.
10
Kaiser Permanente Center for Health Research, Atlanta, GA, United States.
11
Department of Research and Evaluation, Kaiser Permanente of Southern California, Pasadena, United States.

Abstract

The Vaccine Safety Datalink (VSD) is a collaborative project between the Centers for Disease Control and Prevention (CDC) and 9 health care organizations. Established in 1990, VSD is a vital resource informing policy makers and the public about the safety of vaccines used in the United States. Large linked databases are used to identify and evaluate adverse events in over 9 million individuals annually. VSD generates rapid, important safety assessments for both routine vaccinations and emergency vaccination campaigns. VSD monitors safety of seasonal influenza vaccines in near-real time, and provided essential information on the safety of influenza A (H1N1) 2009 monovalent vaccine during the recent pandemic. VSD investigators have published important studies demonstrating that childhood vaccines are not associated with autism or other developmental disabilities. VSD prioritizes evaluation of new vaccines; searches for possible unusual health events after vaccination; monitors vaccine safety in pregnant women; and has pioneered development of biostatistical research methods.

KEYWORDS:

Immunization; Surveillance; Vaccine safety

PMID:
25108215
DOI:
10.1016/j.vaccine.2014.07.073
[Indexed for MEDLINE]

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