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Arch Neurol. 1989 Nov;46(11):1222-4.

A new sign of neurofibromatosis on magnetic resonance imaging of children.

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Department of Radiology, Oregon Health Sciences University, Portland 97201.


Ten pediatric patients with clinically proved neurofibromatosis underwent magnetic resonance imaging of the brain. Seven of these patients had lesions of increased signal intensity on T2-weighted images in the globus pallidus, brain stem, or cerebellar white matter. The lesions did not correlate with results of the neurologic examination or with developmental status. These abnormalities most likely represent hamartomas and should be recognized as part of the diagnostic spectrum of neurofibromatosis.

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