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Curr Opin Biotechnol. 2014 Oct;29:171-83. doi: 10.1016/j.copbio.2014.07.002. Epub 2014 Aug 5.

Genomics of cellulolytic bacteria.

Author information

1
Department of Microbiology, Technische Universität München, Emil-Ramann-Str. 4, D-85350 Freising-Weihenstephan, Germany.
2
Department of Microbiology, Technische Universität München, Emil-Ramann-Str. 4, D-85350 Freising-Weihenstephan, Germany; Institute of Molecular Genetics, Russian Academy of Science, Kurchatov Sq. 2, 123182 Moscow, Russia.
3
Department of Microbiology, Technische Universität München, Emil-Ramann-Str. 4, D-85350 Freising-Weihenstephan, Germany. Electronic address: wschwarz@wzw.tum.de.

Abstract

The heterogeneous plant biomass is efficiently decomposed by the interplay of a great number of different enzymes. The enzyme systems in cellulolytic bacteria have been investigated by sequencing and bioinformatic analysis of genomes from plant biomass degrading microorganisms with valuable insights into the variety of the involved enzymes. This broadened our understanding of the biochemical mechanisms of plant polymer degradation and made the enzymes applicable for modern biotechnology. A list of the truly cellulolytic bacteria described and the available genomic information was examined for proteins with cellulolytic and hemicellulolytic capability. The importance of the isolation, characterization and genomic sequencing of cellulolytic microorganisms and their usage for sustainable energy production from biomass and other residues, is emphasized.

PMID:
25104562
DOI:
10.1016/j.copbio.2014.07.002
[Indexed for MEDLINE]

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