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PLoS One. 2014 Aug 6;9(8):e104526. doi: 10.1371/journal.pone.0104526. eCollection 2014.

Molecular analysis of the cold tolerant Antarctic nematode, Panagrolaimus davidi.

Author information

1
British Antarctic Survey, Natural Environment Research Council, Cambridge, United Kingdom.
2
Transdisciplinary Research Integration Center, Research Organization of Information and Systems, Tokyo, Japan; National Institute of Genetics, Mishima, Japan.
3
Department of Biochemistry, University of Otago, Dunedin, New Zealand.
4
Department of Zoology, University of Otago, Dunedin, New Zealand.

Abstract

Isolated and established in culture from the Antarctic in 1988, the nematode Panagrolaimus davidi has proven to be an ideal model for the study of adaptation to the cold. Not only is it the best-documented example of an organism surviving intracellular freezing but it is also able to undergo cryoprotective dehydration. As part of an ongoing effort to develop a molecular understanding of this remarkable organism, we have assembled both a transcriptome and a set of genomic scaffolds. We provide an overview of the transcriptome and a survey of genes involved in temperature stress. We also explore, in silico, the possibility that P. davidi will be susceptible to an environmental RNAi response, important for further functional studies.

PMID:
25098249
PMCID:
PMC4123951
DOI:
10.1371/journal.pone.0104526
[Indexed for MEDLINE]
Free PMC Article

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