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Jpn J Med. 1989 Jul-Aug;28(4):523-6.

Adult Fanconi syndrome in primary amyloidosis with lambda light-chain proteinuria.

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Department of Internal Medicine, Saga Medical School, Japan.


A 57-year-old woman who had had renal amyloidosis with nephrotic syndrome for five years was found to have the Fanconi syndrome and monoclonal lambda light-chain proteinuria. The amyloidosis of this patient was of primary type on the basis of the permanganate-resistant amyloid, the presence of monoclonal light-chain proteinuria, and the absence of clinical and histologic evidence of multiple myeloma. To best of our knowledge, this is the first case report in which primary amyloidosis with monoclonal lambda light-chain proteinuria was accompanied by adult Fanconi syndrome.

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