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J Pediatr Rehabil Med. 2014;7(2):133-42. doi: 10.3233/PRM-140282.

Bone health in children with neuromuscular disorders.

Author information

1
Division of Endocrinology and Diabetes, University of Washington and Seattle Children's Hospital, Seattle, Washington, WA, USA.
2
Department of Rehabilitation Medicine, University of Washington and Seattle Children's Hospital, Seattle, Washington, WA, USA.

Abstract

This paper provides a broad review of bone health issues in children with neuromuscular diseases (NMD). As Duchenne muscular dystrophy is the most common neuromuscular disease of childhood, there is a strong emphasis on this. This paper reviews the incidence of fractures, the degree of the reduced bone mineral density, the risk factors associated with this common problem, and the non-pharmacological and pharmacological treatment options. Recommendations for monitoring and treatment are provided.

KEYWORDS:

Duchenne; Neuromuscular; fracture; spinal muscular atrophy

PMID:
25096865
DOI:
10.3233/PRM-140282
[Indexed for MEDLINE]

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