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Nanoscale. 2014 Sep 21;6(18):10486-94. doi: 10.1039/c4nr03124e. Epub 2014 Aug 6.

Synthetic micro/nanomotors in drug delivery.

Author information

1
Department of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA. josephwang@ucsd.edu.

Abstract

Nanomachines offer considerable promise for the treatment of diseases. The ability of man-made nanomotors to rapidly deliver therapeutic payloads to their target destination represents a novel nanomedicine approach. Synthetic nanomotors, based on a multitude of propulsion mechanisms, have been developed over the past decade toward diverse biomedical applications. In this review article, we journey from the use of chemically powered drug-delivery nanovehicles to externally actuated (fuel-free) drug-delivery nanomachine platforms, and conclude with future prospects and challenges for such practical propelling drug-delivery systems. As future micro/nanomachines become more powerful and functional, these tiny devices are expected to perform more demanding biomedical tasks and benefit different drug delivery applications.

PMID:
25096021
DOI:
10.1039/c4nr03124e
[Indexed for MEDLINE]

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