Multiorgan failure in the serious trauma patient

Med Intensiva. 2014 Oct;38(7):455-62. doi: 10.1016/j.medin.2014.05.004. Epub 2014 Aug 1.
[Article in English, Spanish]

Abstract

Multiorgan failure remains one of the leading causes of late morbidity and mortality after severe trauma. In the early phase, it is related with an uncontrolled hyper-inflammation state, whereas in the late phase (>72 h), septic complications play a major role. We review the underlying pathophysiology, the evaluation with different scales and the clinical factors associated with multiorgan failure, as well as potential treatment options.

Keywords: Clinical scales; Escalas clínicas; Fallo multiorgánico; Multiorgan failure; Severe trauma; Trauma grave.

Publication types

  • Review

MeSH terms

  • Humans
  • Injury Severity Score
  • Multiple Organ Failure / diagnosis
  • Multiple Organ Failure / etiology*
  • Multiple Organ Failure / physiopathology
  • Multiple Organ Failure / therapy
  • Wounds and Injuries / complications*