Format

Send to

Choose Destination
Dtsch Med Wochenschr. 2014 Oct;139(44):2242-7. doi: 10.1055/s-0034-1370275. Epub 2014 Aug 1.

[Chronic pulmonary Aspergillosis. Four exemplary clinical cases and literature overview].

[Article in German]

Author information

1
Medizinische Klinik I, Universitätsklinikum Köln.
2
Institut für Pathologie, Universitätsklinikum Köln.
3
Institut und Poliklinik für Radiologische Diagnostik, Universitätsklinikum Köln.
4
Herzzentrum, Sektion Pneumologie, Universitätsklinikum Köln.
5
Klinik I für Innere Medizin und Center for Integrated Oncology (CIO) Köln-Bonn, Uniklinik Köln; ZKS Köln, BMBF 01KN1106 und Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Universität zu Köln.

Abstract

Chronic pulmonary aspergillosis (CPA) is a rare complication in patients with either mild immunosuppression or various pulmonary diseases. Diagnosis and therapy are challenging because of unspecific symptoms like productive cough, weight loss, fever and haemoptysis. Differential diagnoses are manifold, and CPA is characterized by findings in chest CT and serologic proof of precipitins. Surgery is only recommended for simple aspergillomas. Recurrent prolonged courses of antifungal treatment yield satisfactory short-term outcome, but long-term prognosis is uncertain. We provide an overview of the literature and present four cases to illustrate disease diversity.

PMID:
25084311
DOI:
10.1055/s-0034-1370275
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Georg Thieme Verlag Stuttgart, New York
Loading ...
Support Center