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Lancet Oncol. 2014 Aug;15(9):e404-14. doi: 10.1016/S1470-2045(14)70018-X.

Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology.

Author information

1
Claude-Bernard-Lyon-1 University and Department of Medical Oncology, Centre Léon-Bérard, Lyon, France. Electronic address: jpdroz@orange.fr.
2
Multidisciplinary Oncology Institute, Clinique de Genolier, Genolier, Switzerland.
3
H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
4
Claude-Bernard-Lyon-1 University and Department of Medical Oncology, Centre Léon-Bérard, Lyon, France.
5
Department of Urology, University Hospitals, Leuven, Belgium.
6
Department of Urology, Queen Mary University of London, London, UK.
7
Division of Surgery and Interventional Science, University College London, London, UK.
8
Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece.
9
Irish Cancer Society and University College Dublin, Dublin, Ireland.
10
Department of Urology, RWTH University Aachen, Aachen, Germany.
11
Guy's and St Thomas' NHS Trust, London, UK.
12
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
13
University Hospital, Saint-Etienne, France.
14
Georges Pompidou Hospital, Department of Oncology, Paris, France.
15
University College London Hospitals, London, UK.
16
Uro‑Oncology Clinic, Centre Hospitalier de l'Université de Montreal, Montreal, QC, Canada.

Abstract

In 2010, the International Society of Geriatric Oncology (SIOG) developed treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013, a new multidisciplinary SIOG working group was formed to update these recommendations. The consensus of the task force is that older men with prostate cancer should be managed according to their individual health status, not according to age. On the basis of a validated rapid health status screening instrument and simple assessment, the task force recommends that patients are classed into three groups for treatment: healthy or fit patients who should have the same treatment options as younger patients; vulnerable patients with reversible impairment who should receive standard treatment after medical intervention; and frail patients with non-reversible impairment who should receive adapted treatment.

PMID:
25079103
DOI:
10.1016/S1470-2045(14)70018-X
[Indexed for MEDLINE]
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