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J Virol. 2014 Oct;88(20):12158-62. doi: 10.1128/JVI.01173-14. Epub 2014 Jul 30.

Parvovirus-derived endogenous viral elements in two South American rodent genomes.

Author information

1
Universidad Andres Bello, Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas, Quillota 980, Viña del Mar, Chile gloria.arriagada@unab.cl robert.gifford@glasgow.ac.uk.
2
MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom gloria.arriagada@unab.cl robert.gifford@glasgow.ac.uk.

Abstract

We describe endogenous viral elements (EVEs) derived from parvoviruses (family Parvoviridae) in the genomes of the long-tailed chinchilla (Chinchilla lanigera) and the degu (Octodon degus). The novel EVEs include dependovirus-related elements and representatives of a clearly distinct parvovirus lineage that also has endogenous representatives in marsupial genomes. In the degu, one dependovirus-derived EVE was found to carry an intact reading frame and was differentially expressed in vivo, with increased expression in the liver.

PMID:
25078696
PMCID:
PMC4178727
DOI:
10.1128/JVI.01173-14
[Indexed for MEDLINE]
Free PMC Article

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