[Role of glycogen synthase kinase-3β in the pathogenesis of mental disorders]

S A Ivanova; I S Losenkov; N A Bokhan

[Role of glycogen synthase kinase-3β in the pathogenesis of mental disorders]

Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(6):93-100.

[Article in Russian]

Authors

S A Ivanova, I S Losenkov, N A Bokhan

PMID: 25075421

Abstract

The literature review contains data about functions of glycogen synthase kinase-313 (GSK-313) in the cell and its role in the functioning of the nervous tissue, an analysis of current research on the participation of GSK-313 in the pathogenesis of affective disorders and schizophrenia and effect of psychotropic drugs on the activity of the kinase.

Publication types

Review

MeSH terms

Glycogen Synthase Kinase 3 / genetics
Glycogen Synthase Kinase 3 / metabolism*
Glycogen Synthase Kinase 3 beta
Humans
Molecular Targeted Therapy
Mood Disorders / drug therapy
Mood Disorders / enzymology*
Mood Disorders / genetics
Polymorphism, Genetic
Psychotropic Drugs / pharmacology
Psychotropic Drugs / therapeutic use
Schizophrenia / drug therapy
Schizophrenia / enzymology*
Schizophrenia / genetics

Substances

Psychotropic Drugs
GSK3B protein, human
Glycogen Synthase Kinase 3 beta
Glycogen Synthase Kinase 3