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J Integr Med. 2014 Jul;12(4):359-66. doi: 10.1016/S2095-4964(14)60025-X.

Effects of cinnamon on perineal pain and healing of episiotomy: a randomized placebo-controlled trial.

Author information

1
Students Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
2
Iranian Center for Evidence Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; E-mail:alizades@tbzmed.ac.ir,smoalch@yahoo.com.
3
Midwifery Department, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
4
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
5
Women Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Abstract

BACKGROUND:

Analgesic and wound-healing effects of cinnamon, a widely used spice, have been shown in laboratory rats. However, we found no human studies in this area.

OBJECTIVE:

The aim of this study was to assess the effect of cinnamon on perineal pain and healing of episiotomy incision.

DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS:

In this double-blind, randomized, placebo-controlled trial, 144 postpartum women were allocated into two groups, using stratified block randomization, 1 h after completion of episiotomy repair. They received cinnamon or placebo ointment, 2 mL every 12 h for 10 d.

MAIN OUTCOME MEASURES:

Perineal pain and wound healing were assessed using visual analogue scale (0-10) and Redness, Edema, Ecchymosis, Discharge, Approximation scale (0-15), respectively. General linear model was used to compare the groups on the outcomes adjusted for baseline values and stratified factors.

RESULTS:

Follow-up rate was 100% up to the 8 h time point in both groups, and 86% (62 of 72) in the cinnamon group and 85% (61 of 72) in the placebo group at day 10-11 after delivery. Pain score in the cinnamon group was significantly lower than that in the placebo group at (4±1) h (adjusted difference: -0.6, 95% confidence interval: -1.0 to -0.2) and (8±1) h (-0.9, -1.4 to -0.3) after intervention, and on the 10-11th day after delivery (-1.4, -2.0 to -0.7). Also the cinnamon group showed significantly more improvement than the control group in healing score at (8±1) h (-0.2, -0.4 to -0.04) and the 10-11th day after delivery (-1.6, -2.0 to -1.1).

CONCLUSION:

Cinnamon can be used for reducing perineal pain and improving healing of episiotomy incision.

PMID:
25074885
DOI:
10.1016/S2095-4964(14)60025-X
[Indexed for MEDLINE]

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