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Epilepsia. 1989 Sep-Oct;30(5):547-58.

Neuroimaging in patients with seizures of probable frontal lobe origin.

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VA Southwest Regional Program, West Los Angeles VA Medical Center (Wadsworth), CA 90073.


Twenty-two patients whose electroclinical ictal characteristics suggested frontal lobe seizure foci were studied. Computed tomography (CT) scans showed abnormalities in only 32% of patients whereas magnetic resonance imaging was informative in 45%. 18FDG-Positron emission tomography (PET) scanning revealed decreased metabolism in 64% of the group. The areas of hypometabolism were focal, regional, or hemispheric. Focal frontal hypometabolism was significantly correlated with the electroclinical (semiologic) ictal localization. Therefore, FDG-PET scanning is a sensitive and specific technique for investigating patients with seizures of probable frontal lobe origins.

[Indexed for MEDLINE]

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