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Am J Dermatopathol. 2015 Jul;37(7):567-9. doi: 10.1097/DAD.0000000000000185.

Primary Cutaneous Gamma-Delta T-Cell Lymphoproliferative Disorder in a 3-Year-Old Boy.

Author information

1
Departments of *Pathology, †Pediatric Hematology and Oncology, and ‡Dermatology, Stanford University Medical Center, Stanford, CA.

Abstract

Primary cutaneous gamma-delta T-cell lymphoma (PCGD-TCL) is a rare disorder, constituting less than 1% of primary cutaneous lymphomas. Most cases occur in adults and may present as plaques or nodules with ulceration. Here we describe an unusual case of PCGD-TCL in a 3-year-old boy who presented with asymptomatic subcutaneous nodules. To our knowledge, this report represents one of the youngest reported patients with gamma-delta lymphoma/lymphoproliferative disorder. In addition, our patient has an indolent clinical presentation with greater than 1 year clinical follow-up. Because gamma-delta T-cell lymphomas are exceedingly rare in children, we acknowledge that the clinical course/outcome in young patients is still unclear. We hope to add to the recognition that PCGD-TCLs demonstrate a wide clinical spectrum of disease with relatively indolent presentations in some cases.

PMID:
25072685
DOI:
10.1097/DAD.0000000000000185
[Indexed for MEDLINE]

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