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J Clin Pharm Ther. 2014 Oct;39(5):455-6. doi: 10.1111/jcpt.12192. Epub 2014 Jul 29.

'Selective' COX-1 or COX-2 NSAIDs: time to change a misleading measure.

Author information

1
Temple University School of Pharmacy, Philadelphia, PA, USA. robert.raffa@temple.edu.

Abstract

The ongoing important debate about the relative benefits/risks of COX-1 or COX-2 NSAIDs is hampered by the use of a measure of 'selectivity' that is inherently flawed. An alternative measure provides more meaningful and clinically relevant information.

PMID:
25070498
DOI:
10.1111/jcpt.12192
[Indexed for MEDLINE]

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