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Arq Neuropsiquiatr. 2014 Jul;72(7):510-6.

Small calcified lesions suggestive of neurocysticercosis are associated with mesial temporal sclerosis.

Author information

1
Departamento de Neurologia, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, SP, Brazil.
2
Laboratório de Investigações Médicas 44, Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina de São Paulo, Sao Paulo, SP, Brazil.
3
Departamento de Bioestatística, Instituto de Biociências, Campus de Botucatu Distrito de Rubião Júnior, Universidade Estadual Paulista ?Júlio de Mesquita Filho?, Botucatu, SP, Brazil.
4
Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina de São Paulo, Sao Paulo, SP, Brazil.

Abstract

Recent studies have suggested a possible relationship between temporal lobe epilepsy with mesial temporal sclerosis (MTS) and neurocysticercosis (NC). We performed a case-control study to evaluate the association of NC and MTS.

METHOD:

We randomly selected patients with different epilepsy types, including: MTS, primary generalized epilepsy (PGE) and focal symptomatic epilepsy (FSE). Patients underwent a structured interview, followed by head computed tomography (CT). A neuroradiologist evaluated the scan for presence of calcified lesions suggestive of NC. CT results were matched with patients' data.

RESULTS:

More patients in the MTS group displayed calcified lesions suggestive of NC than patients in the other groups (p=0.002). On multivariate analysis, MTS was found to be an independent predictor of one or more calcified NC lesions (p=0.033).

CONCLUSION:

After controlling for confounding factors, we found an independent association between NC calcified lesions and MTS.

PMID:
25054983
[Indexed for MEDLINE]
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