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An Bras Dermatol. 2014 Jul-Aug;89(4):609-15.

Sample size: how many participants do I need in my research?

Author information

1
Latin American Cooperative Oncology Group, Porto Alegre, RS, Brazil.
2
Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
3
Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.

Abstract

The importance of estimating sample sizes is rarely understood by researchers, when planning a study. This paper aims to highlight the centrality of sample size estimations in health research. Examples that help in understanding the basic concepts involved in their calculation are presented. The scenarios covered are based more on the epidemiological reasoning and less on mathematical formulae. Proper calculation of the number of participants in a study diminishes the likelihood of errors, which are often associated with adverse consequences in terms of economic, ethical and health aspects.

PMID:
25054748
PMCID:
PMC4148275
[Indexed for MEDLINE]
Free PMC Article

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