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Curr Biol. 2014 Jul 21;24(14):R658-R659. doi: 10.1016/j.cub.2014.05.074.

Tumor models: tumor-stroma interactions drive neoplastic transformation in Drosophila.

Author information

1
ICREA and Institute for Research in Biomedicine, Parc Cientific de Barcelona, Baldiri Reixac, 10-12, 08028 Barcelona, Spain. Electronic address: marco.milan@irbbarcelona.org.

Abstract

Stromal cells play a supportive role in the initiation and progression of carcinomas. A new study in Drosophila implicates mesenchymal cells in supporting EGF receptor-driven tumor growth and cellular transformation of epithelial tissues.

PMID:
25050966
DOI:
10.1016/j.cub.2014.05.074
[Indexed for MEDLINE]
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