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ScientificWorldJournal. 2014;2014:857292. doi: 10.1155/2014/857292. Epub 2014 Jun 23.

Traditional uses, chemical constituents, and biological activities of Bixa orellana L.: a review.

Author information

1
Laboratory of Pharmaceutical Technology, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil.
2
Department of Pharmacy, Federal University of Rio Grande do Norte, 59010-180 Natal, RN, Brazil.
3
Department of Molecular Biology, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil.
4
State Company of Agricultural Research of Paraíba, Rua Eurípedes Tavares 210, Tambiá, 58013-290 João Pessoa, PB, Brazil.
5
Department of Chemistry, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil.

Abstract

Bixa orellana L., popularly known as "urucum," has been used by indigenous communities in Brazil and other tropical countries for several biological applications, which indicates its potential use as an active ingredient in pharmaceutical products. The aim of this work was to report the main evidence found in the literature, concerning the ethnopharmacology, the biological activity, and the phytochemistry studies related to Bixa orellana L. Therefore, this work comprises a systematic review about the use of Bixa orellana in the American continent and analysis of the data collected. This study shows the well-characterized pharmacological actions that may be considered relevant for the future development of an innovative therapeutic agent.

PMID:
25050404
PMCID:
PMC4094728
DOI:
10.1155/2014/857292
[Indexed for MEDLINE]
Free PMC Article

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