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Photodiagnosis Photodyn Ther. 2004 Sep;1(2):157-71. doi: 10.1016/S1572-1000(04)00039-0.

Photodynamic therapy for chest wall recurrence from breast cancer.

Author information

1
Radiation Oncology Department, Brody School of Medicine, East Carolina University, Greenville, NC, USA; PDT Center, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
2
School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY, USA.
3
Physics Department, University of São Paulo-São Carlos, São Carlos, SP, Brazil.
4
PDT Center, Brody School of Medicine, East Carolina University, Greenville, NC, USA; Pulmonary and Critical Care Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
5
PDT Center, Brody School of Medicine, East Carolina University, Greenville, NC, USA; Physics Department, Thomas Harriot College of Arts and Sciences, East Carolina University, Greenville, NC, USA.
6
PDT Center, Brody School of Medicine, East Carolina University, Greenville, NC, USA; Surgical Oncology Department, Brody School of Medicine, East Carolina University, Greenville, NC, USA.

Abstract

Breast cancer is common with over 230,000 new cases diagnosed each year in North America alone. While great strides have been made to achieve excellent cancer control and survival, a significant minority of patients fail locally. While initial salvage to regain disease control is of the utmost importance, it is not universally successful. This leads to a therapeutic quagmire. Additional surgery, radiation and chemo-hormonal therapy are possible, but they are usually highly morbid with low success rates. Photodynamic therapy appears to be an underutilized salvage modality for this unfortunate patient population. This report analyzes and reviews the role of photodynamic therapy for patients with chest wall re-recurrence from breast cancer.

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