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Detection of extended broad-spectrum beta-lactamases in Enterobacteriaceae in four French hospitals.

Author information

1
Service de Bactériologie, Hôpital Henri Mondor, Créteil, France.

Abstract

In 210 strains of Enterobacteriaceae which were isolated in four hospitals and which showed reduced susceptibility to cefotaxime, high synergy was demonstrated between amoxicillin (20 micrograms) + clavulanate (10 micrograms) and cefotaxime (30 micrograms) using a simple double-disk test. Isoelectric focusing on gel and specific iodometric detection using ceftriaxone identified four extended broad-spectrum beta-lactamases (isoelectric points 7.6, 6.3, 7.0 and 5.9) produced by the strains.

PMID:
2504594
[Indexed for MEDLINE]

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