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World J Orthop. 2014 Jul 18;5(3):373-8. doi: 10.5312/wjo.v5.i3.373. eCollection 2014 Jul 18.

Partial anterior cruciate ligament tears treated with intraligamentary plasma rich in growth factors.

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Roberto Seijas, Oscar Ares, Xavier Cuscó, Pedro Álvarez, Ramón Cugat, Department of Orthopaedic Surgery, Fundación García Cugat, Hospital Quirón Barcelona, 08023 Barcelona, Spain.



To evaluate the effect of the application of plasma rich in growth factors (PRGF)-Endoret to the remaining intact bundle in partial anterior cruciate ligament (ACL) tears.


A retrospective review of the rate of return to play in football players treated with the application of PRGF-Endoret in the remaining intact bundle in partial ACL injuries that underwent surgery for knee instability. Patients with knee instability requiring revision surgery for remnant ACL were selected. PRGF was applied in the wider part of posterolateral bundle and the time it took patients to return to their full sporting activities at the same level before the injury was evaluated.


A total of 19 patients were reviewed. Three had a Tegner activity level of 10 and the remaining 16 level 9. The time between the injury and the time of surgery was 5.78 wk (SD 1.57). In total, 81.75% (16/19) returned to the same pre-injury level of sport activity (Tegner 9-10). 17 males and 2 females were treated. The rate of associated injury was 68.42% meniscal lesions and 26.31% cartilage lesions. The KT-1000 values were normalized in all operated cases. One patient was not able to return to sport due to the extent of their cartilage lesions. The 15 patients with Tegner activity level 9 returned to play at an average of 16.20 wk (SD 1.44) while the 3 patients with Tegner activity level 10 did so in 12.33 wk (SD 1.11).


With one remaining intact bundle the application of PRGF-Endoret in instability cases due to partial ACL tear showed high return to sport rates at pre- injury level in professional football players.


Anterior cruciate ligament; Partial tears anterior cruciate ligament; Plasma rich in growth factors; Platelet-rich plasma

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